Health and Wellness
May 31, 2025

hsCRP: The Low-Level Inflammation Biomarker You Need to Know

WRITTEN BY
Rosa Tsoukala
Co-Founder & Chief Scientist

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hsCRP: The Low-Level Inflammation Biomarker You Need to Know

When we hear about inflammation, we often imagine visible redness or swelling after a bruise or cut. Yet not all inflammation is so obvious. Long before symptoms appear, your body may be dealing with a low-level inflammatory process that quietly raises the risk for chronic conditions like heart disease, type 2 diabetes, or even certain autoimmune disorders. One of the most effective ways to spot low-grade inflammation early is through high-sensitivity C-reactive protein (hsCRP) testing.

What Exactly Is hsCRP?

CRP, or C-reactive protein, is produced by the liver in response to inflammation. Doctors have used standard CRP tests for decades, usually to gauge acute infections or track significant inflammatory flare-ups. The difference with hsCRP lies in its sensitivity. This test can detect much lower levels of CRP, making it particularly useful for spotting subtle, chronic inflammation that might not trigger obvious symptoms.

Why Does Chronic Inflammation Matter?

Persistent low-level inflammation can gradually strain the body’s systems. Over time, it can disrupt blood vessel function, contribute to the formation of atherosclerotic plaques, and compromise insulin sensitivity. That’s why elevated hsCRP has been linked with an increased risk of cardiovascular events, such as heart attacks, and may also indicate a heightened risk for other inflammatory-related illnesses.

How Is It Used in Practice?

A higher hsCRP reading doesn’t automatically mean you’re on the brink of serious disease; rather, it highlights the need to look more closely at factors like diet, exercise habits, and stress levels. For instance, elevated hsCRP taken together with other biomarkers like detailed lipid analysis and blood glucose, helps pinpoint the causes behind inflammation.

Getting a Full Picture

While hsCRP is a powerful biomarker, it’s most informative when viewed along with other markers such as blood glucose, lipids, or ApoB and with a thorough health history in hand. If you do find your hsCRP levels elevated, it’s important not to panic. Instead, consider it a prompt to investigate possible triggers and make targeted changes that support long-term health.

Where Kyma Health Fits In

At Kyma Health, we recognize the significance of even subtle inflammatory signals. That’s why hsCRP, along with additional advanced biomarkers, forms part of our comprehensive health panel. By assessing a variety of markers side by side, we strive to catch warning signs early and personalize a roadmap that addresses the root causes of inflammation, from dietary adjustments to stress-reduction strategies.

Understanding hsCRP and its role in revealing low-level inflammation can be a game-changer for preventive health. Rather than waiting for major symptoms or complications, monitoring this biomarker offers an opportunity to take proactive steps—be it diet, exercise, or broader lifestyle changes—to keep your body resilient and reduce your risk of chronic disease over the long run.

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